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Clinicians should screen for eating disorders prior to prescribing, discuss risks transparently, monitor patients closely, and prioritize long-term recovery over short-term weight outcomes
That signaling bias inhibits receptor internalization the process by which receptors are pulled back inside cells and become temporarily unavailable which is thought to prolong efficacy and may contribute to the drug's tolerability profile by reducing receptor desensitization
E., Rosenstock, J., & Gerstein, H
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No, yeast infections are not listed as a recognized side effect in FDA prescribing information for Zepbound, and clinical trials did not identify them as a statistically significant adverse event directly attributable to tirzepatide
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